The Museum's collections hold thousands of objects related to chemistry, biology, physics, astronomy, and other sciences. Instruments range from early American telescopes to lasers. Rare glassware and other artifacts from the laboratory of Joseph Priestley, the discoverer of oxygen, are among the scientific treasures here. A Gilbert chemistry set of about 1937 and other objects testify to the pleasures of amateur science. Artifacts also help illuminate the social and political history of biology and the roles of women and minorities in science.
The mathematics collection holds artifacts from slide rules and flash cards to code-breaking equipment. More than 1,000 models demonstrate some of the problems and principles of mathematics, and 80 abstract paintings by illustrator and cartoonist Crockett Johnson show his visual interpretations of mathematical theorems.